Pioneering a Restorative Approach

Heart valve disease is a serious condition. In industrialized countries, it affects around 2% of the population and many patients remain undiagnosed.

In these countries, hundreds of thousands of patients undertake heart valve intervention every year. This figure is expected to rise substantially due to aging of the population and better diagnosis of pre-existing heart valve disease.

Biological and mechanical heart valves can be life savers. However, all existing options involve some compromise. Patients with biological valves may endure repeated replacement procedures. Mechanical valves require long-term medication, with potentially severe side effects.

Xeltis is pioneering a restorative approach in heart valve therapy to overcome the limitations of existing options.

Xeltis’ heart valves enable the patient’s own body to naturally restore a new heart valve through a therapeutic approach called Endogenous Tissue Restoration (ETR).

Xeltis’ history is the culmination of substantial developments in regenerative medicine, supramolecular chemistry and electrospinning.


Xeltis is carrying the legacy of hundreds of years of research made by incredible visionaries and scientists.

Most of the (contemporary) people named are today involved with the company.

Scientific Literature

    Academic Partnerships

    Xeltis is actively involved in research collaborations with leading academic partners. Scientific research projects enable Xeltis to increase our knowledge of ETR, by leveraging the deep scientific understanding achieved at an academic level, and to contribute to our robust knowledge of technology application in the field.

    Xeltis Academic Partnerships include among others: